Cetaphil
$34.92 · Cleanser
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Community
Not enough reports yet (0/3).
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Cetyl Alcohol and Stearyl Alcohol)
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Key actives
Aqua, Cetyl Alcohol, Propylene Glycol, Sodium Lauryl Sulfate, Stearyl Alcohol, Polysorbate 20, Methyl Paraben, Propyl Paraben, Butylparaben
19 studies on 9of this product’s ingredients. These study the ingredient, not this product.
Contact Dermatitis, 1995 · systematic-review
Comprehensive review establishing SLS as the model irritant: mechanisms include protein denaturation of stratum corneum keratins, solubilization of intercellular lipid lamellae, direct keratinocyte cytotoxicity, and IL-1α release triggering inflammatory cascade; barrier recovery takes 5-7 days after single 24-hour SLS exposure
Contact Dermatitis, 2003 · n=50 · rct
Irritant patch-test profile of detergents found sodium lauryl sulfate (SLS) produced the strongest irritant reactions versus sodium laureth sulfate and alkyl polyglucoside, supporting SLS as the most irritant of these common detergents and its use as the reference irritant.
Journal of Investigative Dermatology, 1990 · n=20 · rct
Classic dose-response study (n=20): SLS produced concentration-dependent irritant contact dermatitis; TEWL increased linearly with SLS concentration (0.25-2%); barrier disruption was detectable at concentrations as low as 0.5% with 24-hour occlusion; established the gold standard SLS patch test methodology
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Community outcomes are self-reported member experiences, shown separately from the evidence score — never blended into it. Educational, not medical advice.