Clinique
$51.00 · Serum
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Key actives
Water\Aqua\Eau, Glycerin, Butylene Glycol, Phenyl Trimethicone, Propanediol, Sucrose, Hydroxyethyl Urea, Alteromonas Ferment Extract, Hydrolyzed Rice Extract, Acetyl Glucosamine, Trehalose, Algae Extract, Caffeine, Cholesterol, Aloe Barbadensis Leaf Water, Sodium Hyaluronate, Pentaerythrityl Tetraethylhexanoate, Dextrin Palmitate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitol, Sodium Polyaspartate, Tocopheryl Acetate, Carbomer, Dehydroxanthan Gum, Citric Acid, Tetrahexyldecyl Ascorbate, Benzophenone-4, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Sodium Citrate, Disodium EDTA, BHT, Chlorphenesin, Phenoxyethanol, Red 4 (Ci 14700), Yellow 5 (Ci 19140)
52 studies on 17of this product’s ingredients. These study the ingredient, not this product.
Clinics in Dermatology, 2012 · systematic-review
Review of how moisturizers affect the epidermal barrier: humectants such as glycerin increase stratum corneum hydration and can strengthen barrier function and resistance to irritation, although effects depend on formulation and some moisturizers may weaken the barrier; supports well-formulated glycerin-containing emollients for dry, barrier-impaired skin.
British Journal of Dermatology, 2008 · systematic-review
Review establishing glycerin as the gold standard humectant: attracts water to stratum corneum via hydrogen bonding, improves skin mechanical properties (elasticity, pliability), enhances desmosome degradation for smooth desquamation, and modulates aquaporin-3 channels; effective at 2-20% in topical formulations
Dermatologic Therapy, 2004 · systematic-review
Comprehensive review of moisturization mechanisms: glycerin contributes to corneocyte hydration by replacing lost natural moisturizing factor (NMF) components; maintains stratum corneum fluidity at low humidity; superior humectant performance vs propylene glycol, sorbitol, and urea in controlled comparisons
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Community outcomes are self-reported member experiences, shown separately from the evidence score — never blended into it. Educational, not medical advice.