barrier lipid
| Concern | Strength | Studies | What the research says |
|---|---|---|---|
| Dryness | Strong | 2 | Using cyanoacrylate stripping and thin-layer chromatography in 47 atopic dermatitis patients versus 20 healthy controls, atopic skin showed reduced total ceramides (especially ceramide 1) relative to its cholesterol… |
No known conflicts — Cholesterol isn’t flagged against any concern or skin condition.
Strength reflects the ingredient’s effect on each concern; study counts match research whose findings relate to that concern.
Cholesterol is a barrier lipid backed by a moderate body of supporting evidence (evidence tier 2 of 4). We track 2 studies for it.
Acta Dermato-Venereologica · 1998 · observational · n=67
Using cyanoacrylate stripping and thin-layer chromatography in 47 atopic dermatitis patients versus 20 healthy controls, atopic skin showed reduced total ceramides (especially ceramide 1) relative to its cholesterol content, linking altered stratum-corneum ceramide/cholesterol lipid composition to impaired barrier function and dryness.
Journal of Dermatological Science · 2015 · observational
Comparing normal, atopic-dermatitis lesional and non-lesional skin, the study measured stratum-corneum ceramides, free fatty acids and cholesterol and related the ceramide-to-cholesterol and free-fatty-acid-to-cholesterol ratios to barrier function (transepidermal water loss), underscoring cholesterol's role within the stratum-corneum barrier-lipid balance.
In 800 products — most often moisturizers (313), serums (242), cleansers (61), from $3.20 to $476.25. Set up a profile to rank these for your skin. Click any product to learn more.
Saturday Skin
Rub-A-Dub Refining Peel Gel Exfoliator
Exfoliant
$19.6073.9ml · $0.27/ml
Ideal for
Not recommended for
Saturday Skin
Rub-A-Dub Refining Peel Gel Exfoliator
Exfoliant
$19.6073.9ml · $0.27/ml
Ideal for
Not recommended for
Rub-A-Dub Refining Peel Gel Exfoliator is a exfoliant by Saturday Skin. Key ingredients include Glycerin, Butylene Glycol, Alcohol Denat.
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Nip + Fab
NIP+FAB Ceramide Fix Base Build Moisture Milk 8% 125ml
Moisturizer
$38.04125ml · $0.30/ml
Ideal for
Nip + Fab
NIP+FAB Ceramide Fix Base Build Moisture Milk 8% 125ml
Moisturizer
$38.04125ml · $0.30/ml
Ideal for
NIP+FAB Ceramide Fix Base Build Moisture Milk 8% 125ml is a barrier moisturiser by Nip + Fab. Key ingredients include Niacinamide, Glycerin, Dimethicone.
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Nip + Fab
NIP+FAB Ceramide Fix Serum 12% 50ml
Serum
$37.0850ml · $0.74/ml
Ideal for
Caution
May aggravate: Atopic Dermatitis / Eczema (Azelaic Acid)
Nip + Fab
NIP+FAB Ceramide Fix Serum 12% 50ml
Serum
$37.0850ml · $0.74/ml
Ideal for
Caution
May aggravate: Atopic Dermatitis / Eczema (Azelaic Acid)
NIP+FAB Ceramide Fix Serum 12% 50ml is a brightening serum by Nip + Fab. Key ingredients include Butylene Glycol, Niacinamide, Glycerin.
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Set up your skin profileKate Somerville
DeliKate Recovery Cream - 1.7 oz
Moisturizer
$84.0050.3ml · $1.67/ml
Ideal for
Caution
May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Shea Butter, Glyceryl Stearate and Polysorbate 60)
Kate Somerville
DeliKate Recovery Cream - 1.7 oz
Moisturizer
$84.0050.3ml · $1.67/ml
Ideal for
Caution
May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Shea Butter, Glyceryl Stearate and Polysorbate 60)
DeliKate Recovery Cream - 1.7 oz is a peptide serum by Kate Somerville. Key ingredients include Glycerin, Coco-Caprylate/Caprate, Cetearyl Alcohol.
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Set up your skin profileKate Somerville
Serum
$99.0029.6ml · $3.35/ml
Ideal for
Kate Somerville
Serum
$99.0029.6ml · $3.35/ml
Ideal for
DeliKate Recovery Serum is a antioxidant serum by Kate Somerville. Key ingredients include Glycerin, Butylene Glycol, Propanediol.
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Set up your skin profileBubble
Day Dream Vitamin C + Niacinamide Tone & Texture Serum
Serum
$17.0029.6ml · $0.57/ml
Ideal for
Caution
May aggravate: Seborrheic Dermatitis (Glyceryl Stearate)
Bubble
Day Dream Vitamin C + Niacinamide Tone & Texture Serum
Serum
$17.0029.6ml · $0.57/ml
Ideal for
Caution
May aggravate: Seborrheic Dermatitis (Glyceryl Stearate)
Day Dream Vitamin C + Niacinamide Tone & Texture Serum is a brightening serum by Bubble. Key ingredients include Water, Coco-Caprylate/Caprate, Glycerin.
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Set up your skin profileStriVectin
Multi-Action Hydration Multiplier Hyaluronic Acid Serum
Serum
$69.0029.6ml · $2.33/ml
Ideal for
Caution
May aggravate: Seborrheic Dermatitis (Shea Butter and Glyceryl Stearate); Rosacea (Limonene and Linalool)
StriVectin
Multi-Action Hydration Multiplier Hyaluronic Acid Serum
Serum
$69.0029.6ml · $2.33/ml
Ideal for
Caution
May aggravate: Seborrheic Dermatitis (Shea Butter and Glyceryl Stearate); Rosacea (Limonene and Linalool)
Multi-Action Hydration Multiplier Hyaluronic Acid Serum is a hydrating serum by StriVectin. Key ingredients include Pentylene Glycol, Propanediol, Caprylic/Capric Triglyceride.
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Set up your skin profileRODAN + FIELDS
Active Hydration Face Serum With Hyaluronic Acid
Serum
$110.0029.6ml · $3.72/ml
Ideal for
Not recommended for
Caution
May aggravate: Psoriasis (Lactic Acid and Fragrance); Melasma (Fragrance); Seborrheic Dermatitis (Cetyl Alcohol); Perioral Dermatitis (Fragrance)
RODAN + FIELDS
Active Hydration Face Serum With Hyaluronic Acid
Serum
$110.0029.6ml · $3.72/ml
Ideal for
Not recommended for
Caution
May aggravate: Psoriasis (Lactic Acid and Fragrance); Melasma (Fragrance); Seborrheic Dermatitis (Cetyl Alcohol); Perioral Dermatitis (Fragrance)
Active Hydration Face Serum With Hyaluronic Acid is a exfoliant by RODAN + FIELDS. Key ingredients include Glycerin, Pentylene Glycol, Hyaluronic Acid.
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Set up your skin profileBubble
Cosmic Silk Hydrating Milky Toner
Cleanser
$16.00100.5ml · $0.16/ml
Ideal for
Not recommended for
Bubble
Cosmic Silk Hydrating Milky Toner
Cleanser
$16.00100.5ml · $0.16/ml
Ideal for
Not recommended for
Cosmic Silk Hydrating Milky Toner is a water cleanser by Bubble. Key ingredients include Glycerin, Coco-Caprylate/Caprate, Linoleic Acid.
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Set up your skin profileRoC
Retinol Correxion Deep Wrinkle Rich Cream Moisturizer
Moisturizer
$37.9950.3ml · $0.76/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Cetyl Alcohol and Isopropyl Palmitate)
RoC
Retinol Correxion Deep Wrinkle Rich Cream Moisturizer
Moisturizer
$37.9950.3ml · $0.76/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Cetyl Alcohol and Isopropyl Palmitate)
Retinol Correxion Deep Wrinkle Rich Cream Moisturizer is a retinoid treatment by RoC. Key ingredients include Water, Glycerin, Glyceryl Stearate SE.
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Set up your skin profileEducational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.