Shiseido
$89.00 · Serum
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Caution
May aggravate: Seborrheic Dermatitis (Shea Butter); Perioral Dermatitis (Petrolatum and Fragrance)
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A powerful serum clinically proven to improve the appearance of dark spots and wrinkles, in as soon as two weeks.*¹ This multi-benefit solution delivers intensive efficacy on dullness, uneven skin tone and texture for all skin types, including sensitive and acne-prone.
Formulated with Picão Preto Extract, a gentle, plant-based retinol alternative. This powerful ingredient helps reduce the appearance of wrinkles and roughness.iacinamide, a form of Vitamin B3 known for its many skincare benefits, helps to reduce the appearance of hyperpigmentation and minimize age spots while strengthening skin's barrier and overall condition.Combined together, these
Picão Preto Extract: A gentle, plant-based retinol alternative that helps reduce the appearance of wrinkles and roughness.Niacinamide: A form of Vitamin B3, this ingredient is known for its multiple
A powerful serum clinically proven to improve the appearance of dark spots and wrinkles, in as soon as two weeks.*¹ This multi-benefit solution delivers intensive efficacy on dullness, uneven skin tone and texture for all skin types, including sensitive and acne-prone.DetailsBenefitsFormulated with Picão Preto Extract, a gentle, plant-based retinol alternative. This powerful ingredient helps reduce the appearance of wrinkles and roughness.iacinamide, a form of Vitamin B3 known for its many skincare
Apply morning and evening to cleansed skin.Pump twice and massage onto face until fully absorbed.For best results, follow with Benefiance Brightening and Wrinkle Smoothing Cream.IngredientsWater/Aqua/Eau, Alcohol Denat., Dipropylene Glycol, Dimethicone, Pentaerythrityl Tetraethylhexanoate, Glycerin, Niacinamide, Butyrospermum Parkii (Shea) Butter, Petrolatum, Hydrogenated Polydecene, Phytosteryl Macadamiate, Behenyl Alcohol, Peg/Ppg-14/7 Dimethyl Ether, Potassium Methoxysalicylate, Silica, Beheneth-20, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Batyl Alcohol, Maltitol, Bidens Pilosa Extract, Chlorphenesin, Polyvinyl Alcohol, Xanthan Gum, Sodium Citrate, Potassium Hydroxide, Dipotassium Glycyrrhizate, Linalool, Disodium Edta, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Sodium Metaphosphate, Limonene, Citrus Limon (Lemon) Peel Oil, Hexamethylindanopyran, Sodium Metabisulfite, Tetramethyl Acetyloctahydronaphthalenes, Citronellol, Geraniol, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Pinene, Crataegus Monogyna Flower Extract, Angelica Keiskei Leaf/Stem Extract, Panax Ginseng Root Extract, Ziziphus Jujuba Fruit Extract, Hydrogenated Polyisobutene, Butylene Glycol, Fragrance (Parfum), Tocopherol, Caffeine, Alcohol, Citric Acid, Citrus Aurantium Peel Oil, Terpineol, Alpinia Speciosa Leaf Extract, Alpha-Isomethyl Ionone, Phenoxyethanol, Linalyl Acetate
BenefitsFormulated with Picão Preto Extract, a gentle, plant-based retinol alternative. This powerful ingredient helps reduce the appearance of wrinkles and roughness.iacinamide, a form of Vitamin B3 known for its many skincare
Key actives
Water/Aqua/Eau, Alcohol Denat., Dipropylene Glycol, Dimethicone, Pentaerythrityl Tetraethylhexanoate, Glycerin, Niacinamide, Butyrospermum Parkii (Shea) Butter, Petrolatum, Hydrogenated Polydecene, Phytosteryl Macadamiate, Behenyl Alcohol, Peg/Ppg-14/7 Dimethyl Ether, Potassium Methoxysalicylate, Silica, Beheneth-20, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Batyl Alcohol, Maltitol, Bidens Pilosa Extract, Chlorphenesin, Polyvinyl Alcohol, Xanthan Gum, Sodium Citrate, Potassium Hydroxide, Dipotassium Glycyrrhizate, Linalool, Disodium Edta, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Sodium Metaphosphate, Limonene, Citrus Limon (Lemon) Peel Oil, Hexamethylindanopyran, Sodium Metabisulfite, Tetramethyl Acetyloctahydronaphthalenes, Citronellol, Geraniol, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Pinene, Crataegus Monogyna Flower Extract, Angelica Keiskei Leaf/Stem Extract, Panax Ginseng Root Extract, Ziziphus Jujuba Fruit Extract, Hydrogenated Polyisobutene, Butylene Glycol, Fragrance (Parfum), Tocopherol, Caffeine, Alcohol, Citric Acid, Citrus Aurantium Peel Oil, Terpineol, Alpinia Speciosa Leaf Extract, Alpha-Isomethyl Ionone, Phenoxyethanol, Linalyl Acetate, Geranyl Acetate, Linum Usitatissimum (Linseed) Seed Oil, Iron Oxides (Ci 77492), Iron Oxides (Ci 77491).
87 studies on 23of this product’s ingredients. These study the ingredient, not this product.
Clinics in Dermatology, 2012 · systematic-review
Review of how moisturizers affect the epidermal barrier: humectants such as glycerin increase stratum corneum hydration and can strengthen barrier function and resistance to irritation, although effects depend on formulation and some moisturizers may weaken the barrier; supports well-formulated glycerin-containing emollients for dry, barrier-impaired skin.
British Journal of Dermatology, 2008 · systematic-review
Review establishing glycerin as the gold standard humectant: attracts water to stratum corneum via hydrogen bonding, improves skin mechanical properties (elasticity, pliability), enhances desmosome degradation for smooth desquamation, and modulates aquaporin-3 channels; effective at 2-20% in topical formulations
Dermatologic Therapy, 2004 · systematic-review
Comprehensive review of moisturization mechanisms: glycerin contributes to corneocyte hydration by replacing lost natural moisturizing factor (NMF) components; maintains stratum corneum fluidity at low humidity; superior humectant performance vs propylene glycol, sorbitol, and urea in controlled comparisons
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Community outcomes are self-reported member experiences, shown separately from the evidence score — never blended into it. Educational, not medical advice.