irritant
Most common cause of cosmetic contact dermatitis. Fragrance mixes contain 50-200+ individual chemicals; oxidation products of terpenes, aldehydes, and balsam compounds act as haptens that trigger T-cell mediated hypersensitivity.
Fragrance is a irritant backed by a large, consistent body of clinical evidence (evidence tier 1 of 4). We track 4 studies for it, 4 reporting a positive effect.
American Journal of Clinical Dermatology · 2003 · systematic review · n=11545
Clinical review of fragrance contact allergy: an estimated 1.7-4.1% of the general population is sensitized to fragrance-mix ingredients and about 10% of patch-tested eczema patients react; fragrance materials occur in 15-100% of cosmetic products; allergy predominates in women with facial or hand eczema.
Environmental Sciences Europe · 2012 · systematic review
Applied EU CLP hazard-classification criteria (EC 1272/2008) to personal care products: nearly all contained ingredients that would trigger hazard labelling—85% for eye effects and 52% for skin effects (including sensitizers such as fragrance allergens)—yet cosmetics are exempt from CLP labelling, leaving consumers under-informed about these hazards.
Contact Dermatitis · 1997 · systematic review
Systematic review establishing fragrance as the leading cause of cosmetic contact dermatitis, responsible for 30-45% of cosmetic adverse reactions; covers both irritant (direct keratinocyte damage) and allergic (hapten-driven type IV hypersensitivity) mechanisms; identifies cinnamal, hydroxycitronellal, and oakmoss as top individual allergens
Dermatitis · 2020 · observational · n=28237
Retrospective analysis of NACDG data 2007-2016 (n=24,246): 22.7% had fragrance- or botanical-related allergy; fragrance mix I (10.6%), Myroxylon pereirae/balsam of Peru (8%) and fragrance mix II (4.9%) were leading allergens, with rising trends for fragrance mix I and II; sensitized patients were more often female and older than 40.
In 3,941 products — most often serums (1205), moisturizers (1161), cleansers (585), from $2.69 to $1786.24. Set up a profile to rank these for your skin. Click any product to learn more.
Moroccanoil
Moroccanoil Treatment Original 100ml
Serum
$48.90100ml · $0.49/ml
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Moroccanoil
Moroccanoil Treatment Original 100ml
Serum
$48.90100ml · $0.49/ml
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Moroccanoil Treatment Original 100ml is a skincare product by Moroccanoil. Key ingredients include Cyclopentasiloxane, Dimethicone, Cyclomethicone.
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ESPA
ESPA Hydrating Cleansing Milk 200ml
Cleanser – for Dryness
$36.83200ml · $0.18/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Sweet Almond Oil and Cetearyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
ESPA
ESPA Hydrating Cleansing Milk 200ml
Cleanser – for Dryness
$36.83200ml · $0.18/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Sweet Almond Oil and Cetearyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
ESPA Hydrating Cleansing Milk 200ml is a water cleanser by ESPA. Key ingredients include Water, Glycerin, Sweet Almond Oil.
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Caudalie
Caudalie Vinoclean Gentle Foam Cleanser 150ml
Cleanser – for Dryness
$17.15150ml · $0.11/ml
Ideal for
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Caudalie
Caudalie Vinoclean Gentle Foam Cleanser 150ml
Cleanser – for Dryness
$17.15150ml · $0.11/ml
Ideal for
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Caudalie Vinoclean Gentle Foam Cleanser 150ml is a water cleanser by Caudalie. Key ingredients include Glycerin, Cocamidopropyl Betaine, Caprylyl Glycol.
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ELEMIS
Elemis Dynamic Resurfacing Facial Pads (14 Pads)
Serum – for Dryness, Dark spots & hyperpigmentation
$25.00
Ideal for
Not recommended for
Caution
May aggravate: Psoriasis (Lactic Acid and Fragrance); Melasma (Fragrance); Perioral Dermatitis (Fragrance); Seborrheic Dermatitis (Shea Butter and Stearyl Alcohol)
ELEMIS
Elemis Dynamic Resurfacing Facial Pads (14 Pads)
Serum – for Dryness, Dark spots & hyperpigmentation
$25.00
Ideal for
Not recommended for
Caution
May aggravate: Psoriasis (Lactic Acid and Fragrance); Melasma (Fragrance); Perioral Dermatitis (Fragrance); Seborrheic Dermatitis (Shea Butter and Stearyl Alcohol)
Elemis Dynamic Resurfacing Facial Pads (14 Pads) is a exfoliant by ELEMIS. Key ingredients include Butylene Glycol, Polysorbate 20, Lactic Acid.
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Eucerin
Eucerin Sun Gel Cream Dry Touch SPF50+ 200ml
Moisturizer
$20.96200ml · $0.10/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Stearyl Alcohol and Glyceryl Stearate); Perioral Dermatitis (Fragrance)
Eucerin
Eucerin Sun Gel Cream Dry Touch SPF50+ 200ml
Moisturizer
$20.96200ml · $0.10/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Stearyl Alcohol and Glyceryl Stearate); Perioral Dermatitis (Fragrance)
Eucerin Sun Gel Cream Dry Touch SPF50+ 200ml is a spf moisturiser by Eucerin. Key ingredients include Water, Homosalate, Alcohol Denat.
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ELEMIS
Elemis Pro-Collagen Energising Marine Cleanser (150ml)
Cleanser
$70.00150ml · $0.47/ml
Ideal for
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance and Lactic Acid); Melasma (Fragrance)
ELEMIS
Elemis Pro-Collagen Energising Marine Cleanser (150ml)
Cleanser
$70.00150ml · $0.47/ml
Ideal for
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance and Lactic Acid); Melasma (Fragrance)
Elemis Pro-Collagen Energising Marine Cleanser (150ml) is a water cleanser by ELEMIS. Key ingredients include Glycerin, Sodium Lauroyl Sarcosinate, Lauryl Glucoside.
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ELEMIS
Elemis Pro-Collagen Marine Cream SPF 30 (50ml)
Sunscreen – for Dryness
$145.0050ml · $2.90/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Cetyl Alcohol and Shea Butter); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
ELEMIS
Elemis Pro-Collagen Marine Cream SPF 30 (50ml)
Sunscreen – for Dryness
$145.0050ml · $2.90/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Cetyl Alcohol and Shea Butter); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Elemis Pro-Collagen Marine Cream SPF 30 (50ml) is a sunscreen by ELEMIS. Key ingredients include Water, Glycerin, Caprylic/Capric Triglyceride.
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Moroccanoil
Moroccanoil Treatment Original 25ml
Serum
$18.4225ml · $0.74/ml
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Moroccanoil
Moroccanoil Treatment Original 25ml
Serum
$18.4225ml · $0.74/ml
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Moroccanoil Treatment Original 25ml is a skincare product by Moroccanoil. Key ingredients include Cyclopentasiloxane, Dimethicone, Cyclomethicone.
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Caudalie
Caudalie Gentle Buffing Cream 75ml
Moisturizer
$29.2175ml · $0.39/ml
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Caudalie
Caudalie Gentle Buffing Cream 75ml
Moisturizer
$29.2175ml · $0.39/ml
Not recommended for
Caution
May aggravate: Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Caudalie Gentle Buffing Cream 75ml is a basic moisturiser by Caudalie. Key ingredients include Caprylyl Glycol, Fragrance, Benzyl Alcohol.
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Estée Lauder
Moisturizer
$57.1550ml · $1.14/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Linoleic Acid, Isopropyl Myristate and Stearyl Alcohol); Perioral Dermatitis (Isopropyl Myristate and Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Estée Lauder
Moisturizer
$57.1550ml · $1.14/ml
Ideal for
Not recommended for
Caution
May aggravate: Seborrheic Dermatitis (Linoleic Acid, Isopropyl Myristate and Stearyl Alcohol); Perioral Dermatitis (Isopropyl Myristate and Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Estée Lauder DayWear Sheer Tint Release Advanced Multi-Protection Anti-Oxidant Moisturizer SPF15 50ml is a spf moisturiser by Estée Lauder. Key ingredients include Octinoxate, Octisalate, Dimethicone.
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Set up your skin profileEducational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.