Emollient and penetration enhancer rated 5/5 on the rabbit ear comedogenicity assay. Promotes follicular hyperkeratinization and microcomedone formation. Widely used in cosmetics as a skin-feel modifier.
The research
Isopropyl Myristate is a comedogenic backed by a moderate body of supporting evidence (evidence tier 2 of 4). We track 2 studies for it, 1 reporting a positive effect.
Journal of the American Academy of Dermatology · 2006 · systematic review
Argues the traditional comedogenicity concept and rabbit ear assay have limited clinical relevance: cosmetic products formulated with ingredients deemed comedogenic (e.g., isopropyl myristate) are not necessarily comedogenic in use; recommends testing finished products on acne-prone human skin rather than relying on raw-ingredient ratings.
Journal of the American Academy of Dermatology · 1984 · observational · n=50
The foundational rabbit ear assay comedogenicity study: isopropyl myristate scored 5/5 (highest comedogenicity), isopropyl palmitate 4/5, coconut oil 4/5, cocoa butter 4/5; established the standard comedogenicity rating scale used in dermatology for 40+ years; identified ester bond structure as a key determinant of comedogenicity
Products with Isopropyl Myristate
In 255 products — most often serums (85), moisturizers (74), sunscreens (51), from $6.35 to $825.50. Set up a profile to rank these for your skin. Click any product to learn more.
May aggravate: Seborrheic Dermatitis (Isopropyl Palmitate and Isopropyl Myristate); Perioral Dermatitis (Isopropyl Myristate)
La Roche-Posay Anthelios UVMune 400 Dermo-Pediatrics Kids Ultra Light Invinsible Fluid SPF 50+ 50ml is a sunscreen by La Roche-Posay. Key ingredients include Bemotrizinol, Alcohol Denat, Ethylhexyl Triazone.
May aggravate: Seborrheic Dermatitis (Isopropyl Myristate); Perioral Dermatitis (Isopropyl Myristate)
Vichy Mineral 89 72H Hyaluronic Acid Daily Fluid SPF50+ Sun Cream 50ml is a sunscreen by Vichy. Key ingredients include Alcohol Denat, Silica, Isopropyl Myristate.
May aggravate: Seborrheic Dermatitis (Isopropyl Myristate); Perioral Dermatitis (Isopropyl Myristate)
VICHY Capital Soleil UV Age Daily SPF 50+ Invisible Sun Cream with Niacinamide 40ml is a sunscreen by Vichy. Key ingredients include Alcohol Denat, Silica, Isopropyl Myristate.
May aggravate: Perioral Dermatitis (Isopropyl Myristate); Rosacea (Linalool)
Elizabeth Arden Eight Hour All-Over Miracle Oil 100ml is a skincare product by Elizabeth Arden. Key ingredients include Isopropyl Myristate, Isopropyl Palmitate, Ethylhexyl Palmitate.
May aggravate: Seborrheic Dermatitis (Isopropyl Myristate); Perioral Dermatitis (Isopropyl Myristate)
Garnier Ambre Solaire Ultra-Light Sensitive Sun Protection Face Fluid SPF50+ 40ml is a sunscreen by Garnier. Key ingredients include Alcohol Denat, Silica, Isopropyl Myristate.
May aggravate: Seborrheic Dermatitis (Isopropyl Myristate, Glyceryl Stearate, Myristic Acid and Palmitic Acid); Perioral Dermatitis (Isopropyl Myristate and Fragrance)
La Roche-Posay Anthelios UVAIR Serum Sunscreen SPF50+ with Hyaluronic Acid, Niacinamide & Vitamin E 50ml is a sunscreen by La Roche-Posay. Key ingredients include Alcohol Denat, Bemotrizinol, Ethylhexyl Triazone.
May aggravate: Seborrheic Dermatitis (Isopropyl Myristate); Perioral Dermatitis (Isopropyl Myristate)
L'Oréal Paris Bright Reveal Dark Spot UV Fluid SPF 50+ with Niacinamide 50ml is a sunscreen by L'Oréal Paris. Key ingredients include Alcohol Denat, Silica, Isopropyl Myristate.