soothing
Allantoin Evidence moderate · Tier 2 Irritation risk Very low In products 1,857
Concerns it helps Concern Strength Studies What the research says Redness & sensitivity Strong 1 In 82 rosacea patients, 8-12 weeks of topical compound heparin sodium allantoin gel significantly reduced Clinician Erythema Assessment and Investigator Global Assessment grades plus burning/itching versus traditional… Dryness Relevant 2 In 82 rosacea patients, 8-12 weeks of topical compound heparin sodium allantoin gel significantly reduced Clinician Erythema Assessment and Investigator Global Assessment grades plus burning/itching versus traditional…
No known conflicts — Allantoin isn’t flagged against any concern or skin condition.
Strength reflects the ingredient’s effect on each concern; study counts match research whose findings relate to that concern.
The research Allantoin is a soothing backed by a moderate body of supporting evidence (evidence tier 2 of 4). We track 8 studies for it, 5 reporting a positive effect.
Read the research — 8 studies Hide the research Journal of the American Academy of Dermatology · 2017 · systematic review
Systematic review: PIVOTAL systematic review consolidating allantoin wound healing mechanism evidence base; documents antioxidant anti inflammatory antimicrobial keratolytic activities plus fibroblast proliferation ECM synthesis granulation tissue epithelialization promotion; identifies evidence base complications due to different formulations used and lack of stability and dermal penetration information in pivotal studies.
Burns · 2009 · rct · n=45
Forty-five postburn hypertrophic scars were randomized to silicone gel, silicone gel sheeting, or topical onion extract with heparin and allantoin for 6 months. All groups significantly improved on the Vancouver Scar Scale, but the silicone products outperformed the allantoin-containing onion extract gel.
Journal of Cosmetic Dermatology · 2025 · rct · n=82
In 82 rosacea patients, 8-12 weeks of topical compound heparin sodium allantoin gel significantly reduced Clinician Erythema Assessment and Investigator Global Assessment grades plus burning/itching versus traditional therapy, while improving skin hydration and lowering transepidermal water loss.
Frontiers in Pharmacology · 2020 · rct
Randomized controlled trial (4 weeks): Patch with Allium cepa extract and allantoin improved pigmentation relief and pliability of C section scars.
Aesthetic Plastic Surgery · 2018 · rct
Randomized controlled trial: Post dermatologic surgery scars RCT for combination product containing allantoin plus onion extract.
International Journal of Women's Dermatology · 2020 · observational · n=31
Clinical study (n=31): Small 2020 study demonstrating allantoin plus ceramide combination acne regimen reduced acne symptoms and improved skin barrier function in 31 women.
+ 2 more studies in our evidence base.
Products with Allantoin In 1,857 products — most often serums (644), moisturizers (488), masks (187), from $2.69 to $564.08 . Set up a profile to rank these for your skin. Click any product to learn more.
CategoryAll (24) Exfoliant (1) Eye Cream (4) Moisturizer (5) Serum (11) Toner (3) Sort byBest match (concern) Price: low to high Value: price per ml Customer reviews Category (A–Z) List Grid
10 of 24 Perricone MD
Perricone MD Neuropeptide Pro-Strength Firming Moisturiser
Moisturizer – for Dryness, Redness & sensitivity
$175.26
★★★★★ ★★★★★ 4.8 (984)
Ideal for
Good Fine lines & wrinkles Good Redness & sensitivity Good Dryness Good Loss of firmness Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Shea Butter, Glyceryl Stearate and Stearyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Perricone MD
Perricone MD Neuropeptide Pro-Strength Firming Moisturiser
Moisturizer – for Dryness, Redness & sensitivity
$175.26
★★★★★ ★★★★★ 4.8 (984)
Ideal for
Good Fine lines & wrinkles Good Redness & sensitivity Good Dryness Good Loss of firmness Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Shea Butter, Glyceryl Stearate and Stearyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Perricone MD Neuropeptide Pro-Strength Firming Moisturiser is a antioxidant serum by Perricone MD. Key ingredients include Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol.
Product Ingredients (36) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Obagi Medical
Obagi Medical Nu-Derm Toner (6.7 oz.)
Toner
$55.00198.1ml · $0.28/ml
★★★★★ ★★★★★ 4.8 (666)
Ideal for
Strong Redness & sensitivity Good Dryness Low Uneven texture Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Seborrheic Dermatitis (Polysorbate 80); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Obagi Medical
Obagi Medical Nu-Derm Toner (6.7 oz.)
Toner
$55.00198.1ml · $0.28/ml
★★★★★ ★★★★★ 4.8 (666)
Ideal for
Strong Redness & sensitivity Good Dryness Low Uneven texture Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Seborrheic Dermatitis (Polysorbate 80); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Obagi Medical Nu-Derm Toner (6.7 oz.) is a hydrating serum by Obagi Medical. Key ingredients include Water, Sodium PCA, Panthenol.
Product Ingredients (6) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Dermalogica
Dermalogica Daily Microfoliant Enzyme Powder 74g
Serum
$82.5574ml · $1.12/ml
★★★★★ ★★★★★ 4.8 (1,261)
Ideal for
Good Oiliness & shine Good Blackheads Good Redness & sensitivity Good Enlarged pores Caution
May aggravate: Atopic Dermatitis / Eczema (Salicylic Acid); Rosacea (Tea Tree Oil, Limonene and Citrus Oils)
Dermalogica
Dermalogica Daily Microfoliant Enzyme Powder 74g
Serum
$82.5574ml · $1.12/ml
★★★★★ ★★★★★ 4.8 (1,261)
Ideal for
Good Oiliness & shine Good Blackheads Good Redness & sensitivity Good Enlarged pores Caution
May aggravate: Atopic Dermatitis / Eczema (Salicylic Acid); Rosacea (Tea Tree Oil, Limonene and Citrus Oils)
Dermalogica Daily Microfoliant Enzyme Powder 74g is a skincare product by Dermalogica. Key ingredients include Colloidal Oatmeal, Allantoin, Salicylic Acid.
Product Ingredients (8) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile NIP+FAB Hyaluronic Fix Extreme4 Hydration Jelly Eye Patches (20 Pairs) is a hydrating serum by Nip + Fab. Key ingredients include Glycerin, Hyaluronic Acid, Xanthan Gum.
Product Ingredients (7) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Obagi Medical
Obagi Medical Hydrate Luxe (1.7 oz.)
Serum – for Dryness, Redness & sensitivity
$85.0050.3ml · $1.69/ml
★★★★★ ★★★★★ 4.7 (678)
Ideal for
Strong Dryness Strong Redness & sensitivity Relevant Fine lines & wrinkles Low Uneven texture Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Seborrheic Dermatitis (Shea Butter, Glyceryl Stearate and Cetyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Obagi Medical
Obagi Medical Hydrate Luxe (1.7 oz.)
Serum – for Dryness, Redness & sensitivity
$85.0050.3ml · $1.69/ml
★★★★★ ★★★★★ 4.7 (678)
Ideal for
Strong Dryness Strong Redness & sensitivity Relevant Fine lines & wrinkles Low Uneven texture Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Seborrheic Dermatitis (Shea Butter, Glyceryl Stearate and Cetyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)
Obagi Medical Hydrate Luxe (1.7 oz.) is a antioxidant serum by Obagi Medical. Key ingredients include Water, Glycerin, Caprylic/Capric Triglyceride.
Product Ingredients (19) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Dermalogica
Dermalogica Daily Microfoliant 13g
Serum
$22.8013ml · $1.75/ml
★★★★★ ★★★★★ 4.7 (496)
Ideal for
Good Oiliness & shine Good Blackheads Good Redness & sensitivity Good Enlarged pores Caution
May aggravate: Atopic Dermatitis / Eczema (Salicylic Acid); Rosacea (Limonene)
Dermalogica
Dermalogica Daily Microfoliant 13g
Serum
$22.8013ml · $1.75/ml
★★★★★ ★★★★★ 4.7 (496)
Ideal for
Good Oiliness & shine Good Blackheads Good Redness & sensitivity Good Enlarged pores Caution
May aggravate: Atopic Dermatitis / Eczema (Salicylic Acid); Rosacea (Limonene)
Dermalogica Daily Microfoliant 13g is a exfoliant by Dermalogica. Key ingredients include Colloidal Oatmeal, Allantoin, Salicylic Acid.
Product Ingredients (7) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile ELEMIS
Elemis Pro-Collagen Morning Matrix (50ml)
Serum
$205.0050ml · $4.10/ml
★★★★★ ★★★★★ 4.7 (632)
Ideal for
Strong Dryness Strong Uneven texture Good Fine lines & wrinkles Good Redness & sensitivity Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Psoriasis (Lactic Acid and Fragrance); Melasma (Fragrance and Menthol); Perioral Dermatitis (Fragrance)
ELEMIS
Elemis Pro-Collagen Morning Matrix (50ml)
Serum
$205.0050ml · $4.10/ml
★★★★★ ★★★★★ 4.7 (632)
Ideal for
Strong Dryness Strong Uneven texture Good Fine lines & wrinkles Good Redness & sensitivity Not recommended for
Atopic Dermatitis / Eczema Rosacea
Caution
May aggravate: Psoriasis (Lactic Acid and Fragrance); Melasma (Fragrance and Menthol); Perioral Dermatitis (Fragrance)
Elemis Pro-Collagen Morning Matrix (50ml) is a exfoliant by ELEMIS. Key ingredients include Glycerin, Propanediol, Butylene Glycol.
Product Ingredients (22) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Allies of Skin
Allies of Skin Peptides Omegas Firming Eye Cream 15 ml.
Eye Cream – for Dryness, Redness & sensitivity
$85.0015ml · $5.67/ml
★★★★★ ★★★★★ 4.7 (645)
Ideal for
Strong Loss of firmness Good Fine lines & wrinkles Good Redness & sensitivity Good Uneven tone & radiance Caution
May aggravate: Seborrheic Dermatitis (Glyceryl Stearate, Argan Oil and Polysorbate 80)
Allies of Skin
Allies of Skin Peptides Omegas Firming Eye Cream 15 ml.
Eye Cream – for Dryness, Redness & sensitivity
$85.0015ml · $5.67/ml
★★★★★ ★★★★★ 4.7 (645)
Ideal for
Strong Loss of firmness Good Fine lines & wrinkles Good Redness & sensitivity Good Uneven tone & radiance Caution
May aggravate: Seborrheic Dermatitis (Glyceryl Stearate, Argan Oil and Polysorbate 80)
Allies of Skin Peptides Omegas Firming Eye Cream 15 ml. is a eye cream by Allies of Skin. Key ingredients include Bakuchiol, Squalane, L-Ascorbic Acid.
Product Ingredients (21) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Medik8 Daily Refresh Balancing Toner 150ml is a brightening serum by Medik8. Key ingredients include Water, Niacinamide, Glycerin.
Product Ingredients (11) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Curél
Curél Moisture Repair Eye Cream 25ml
Eye Cream
$31.7525ml · $1.27/ml
★★★★★ ★★★★★ 4.7 (570)
Ideal for
Good Redness & sensitivity Good Dryness Low Uneven texture Caution
May aggravate: Seborrheic Dermatitis (Cetyl Alcohol)
Curél
Curél Moisture Repair Eye Cream 25ml
Eye Cream
$31.7525ml · $1.27/ml
★★★★★ ★★★★★ 4.7 (570)
Ideal for
Good Redness & sensitivity Good Dryness Low Uneven texture Caution
May aggravate: Seborrheic Dermatitis (Cetyl Alcohol)
Curél Moisture Repair Eye Cream 25ml is a eye cream by Curél. Key ingredients include Glycerin, Dimethicone, Cetyl Alcohol.
Product Ingredients (8) Irritation risk:
Complete your skin profile to see how well this product matches your skin
Set up your skin profile Show next 10
Educational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.
