peptide

Matrixyl (Palmitoyl Pentapeptide-4)

Evidencemoderate · Tier 2Irritation riskVery lowEffective range3–10%In products415

Matrikine peptide fragment that mimics collagen breakdown products; signals fibroblasts to upregulate synthesis of collagen I, III, IV, and fibronectin.

The research

Matrixyl (Palmitoyl Pentapeptide-4) is a peptide backed by a moderate body of supporting evidence (evidence tier 2 of 4). We track 2 studies for it, 2 reporting a positive effect. It is typically effective at 3–10% in a formulation.

Read the research — 2 studies

Products with Matrixyl (Palmitoyl Pentapeptide-4)

In 415 products — most often serums (159), moisturizers (113), eye creams (55), from $5.00 to $1786.24. Set up a profile to rank these for your skin. Click any product to learn more.

10 of 24
SKIN1004

SKIN1004

SKIN1004 Madagascar Centella Poremizing Fresh Ampoule 100ml

Serum

$25.00100ml · $0.25/ml

★★★★★4.9(602)

Ideal for

  • StrongRedness & sensitivity
  • StrongDryness
  • GoodFine lines & wrinkles
  • GoodLoss of firmness

SKIN1004 Madagascar Centella Poremizing Fresh Ampoule 100ml is a peptide serum by SKIN1004. Key ingredients include Centella Asiatica, Water, Butylene Glycol.

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PEACH & LILY

PEACH & LILY

Power Cocktail Lactic Acid Repair Serum

Serum

$51.0029.9ml · $1.71/ml

★★★★★4.8(1,370)

Ideal for

  • ExcellentFine lines & wrinkles
  • StrongDryness
  • GoodUneven texture
  • RelevantDark spots & hyperpigmentation

Caution

May aggravate: Atopic Dermatitis / Eczema (Lactic Acid); Rosacea (Lactic Acid); Psoriasis (Lactic Acid)

Power Cocktail Lactic Acid Repair Serum is a exfoliant by PEACH & LILY. Key ingredients include Water, Lactic Acid, Tromethamine.

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Perricone MD

Perricone MD

Perricone MD Neuropeptide Pro-Strength Firming Moisturiser

Moisturizer – for Dryness, Redness & sensitivity

$175.26

★★★★★4.8(984)

Ideal for

  • GoodFine lines & wrinkles
  • GoodRedness & sensitivity
  • GoodDryness
  • GoodLoss of firmness

Not recommended for

Atopic Dermatitis / EczemaRosacea

Caution

May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol, Shea Butter, Glyceryl Stearate and Stearyl Alcohol); Perioral Dermatitis (Fragrance); Psoriasis (Fragrance); Melasma (Fragrance)

Erborian

Erborian

Erborian Ginseng Super Serum - 30ml

Serum

$50.8030ml · $1.69/ml

★★★★★4.8(858)

Ideal for

  • GoodFine lines & wrinkles
  • GoodDryness
  • RelevantRedness & sensitivity
  • RelevantDark spots & hyperpigmentation

Caution

May aggravate: Rosacea (Linalool)

Erborian Ginseng Super Serum - 30ml is a peptide serum by Erborian. Key ingredients include Propanediol, 1,2-Hexanediol, Butylene Glycol.

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PEACH & LILY

PEACH & LILY

Peptide Pro Firming Moisturizer

Moisturizer

$45.0050ml · $0.90/ml

★★★★★4.7(1,848)

Ideal for

  • StrongFine lines & wrinkles
  • GoodDryness
  • GoodLoss of firmness
  • RelevantRedness & sensitivity

Caution

May aggravate: Seborrheic Dermatitis (Cetearyl Alcohol)

Peptide Pro Firming Moisturizer is a peptide serum by PEACH & LILY. Key ingredients include Water, Butylene Glycol, Glycerin.

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PEACH & LILY

PEACH & LILY

MiniProtein Exosome Bioactive Ampoule

Serum

$53.0029.9ml · $1.77/ml

★★★★★4.8(482)

Ideal for

  • GoodFine lines & wrinkles
  • GoodLoss of firmness
  • GoodRedness & sensitivity
  • RelevantDryness

Caution

May aggravate: Seborrheic Dermatitis (Linoleic Acid and Argan Oil)

MiniProtein Exosome Bioactive Ampoule is a peptide serum by PEACH & LILY. Key ingredients include Water, Butylene Glycol, Coco-Caprylate/Caprate.

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PEACH & LILY

PEACH & LILY

Copper Peptide Pro Firming Serum

Serum

$49.0029.9ml · $1.64/ml

★★★★★4.6(810)

Ideal for

  • StrongFine lines & wrinkles
  • GoodDryness
  • GoodLoss of firmness
  • RelevantRedness & sensitivity

Copper Peptide Pro Firming Serum is a peptide serum by PEACH & LILY. Key ingredients include Water, Dipropylene Glycol, Glycerin.

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Peter Thomas Roth

Peter Thomas Roth

Instant FIRMx Collagen Tightening Eye Patches

Serum

$36.00

★★★★★4.6(864)

Ideal for

  • StrongFine lines & wrinkles
  • StrongRedness & sensitivity
  • GoodDryness
  • GoodLoss of firmness

Instant FIRMx Collagen Tightening Eye Patches is a peptide serum by Peter Thomas Roth. Key ingredients include Glycerin, Cetyl Ethylhexanoate, Dipropylene Glycol.

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Dermalogica

Dermalogica

Dermalogica Age Reversal Eye Complex

Serum – for Acne & breakouts, antioxidant_protection

$87.00

★★★★★4.6(4,540)

Ideal for

  • ExcellentOiliness & shine
  • ExcellentDryness
  • StrongEnlarged pores
  • StrongRedness & sensitivity

Not recommended for

Atopic Dermatitis / EczemaPsoriasis

Caution

May aggravate: Seborrheic Dermatitis (Cetyl Alcohol and Glyceryl Stearate)

Clinique

Clinique

Clinique Smart Clinical Repair™ Overnight Recovery Cream + Mask

Mask – for Dryness, Dark spots & hyperpigmentation

$83.0050ml · $1.88/ml

★★★★★4.6(492)

Ideal for

  • StrongFine lines & wrinkles
  • GoodDryness
  • GoodLoss of firmness
  • RelevantRedness & sensitivity

Caution

May aggravate: Seborrheic Dermatitis (Glyceryl Stearate, Cetearyl Alcohol, Cetyl Alcohol, Sorbitan Oleate and Polysorbate 80); Perioral Dermatitis (Petrolatum)

Clinique Smart Clinical Repair™ Overnight Recovery Cream + Mask is a mask by Clinique. Key ingredients include Glycerin, Butylene Glycol, Glyceryl Stearate.

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Educational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.