Retinoic acid ester that binds retinoid receptors directly without enzymatic conversion. Claimed to deliver retinoid benefits with minimal irritation, though independent evidence is limited.
The research
Hydroxypinacolone Retinoate is a retinoid backed by early but promising evidence (evidence tier 3 of 4). We track 2 studies for it, 2 reporting a positive effect. It is typically effective at 0.1–1% in a formulation.
Encapsulating retinol propionate and hydroxypinacolone retinoate in supramolecular nanoparticles gave high stability, low irritation and sustained release; the formulation significantly increased type I collagen synthesis in human dermal fibroblasts (p<0.01), and facial imaging showed visibly reduced wrinkles over 56 days of use.
Advances in Dermatology and Allergology · 2019 · review · n=40
Review of retinoids in dermatology and cosmetics describing their mechanisms (retinoic-acid-receptor activation, stimulation of collagen synthesis and epidermal renewal) and anti-aging effects; hydroxypinacolone retinoate is a retinoic-acid ester within this retinoid class.
Products with Hydroxypinacolone Retinoate
In 67 products — most often serums (48), moisturizers (11), eye creams (6), from $4.75 to $250.70. Set up a profile to rank these for your skin. Click any product to learn more.
May aggravate: Seborrheic Dermatitis (Shea Butter)
Elizabeth Arden Retinol + HPR Ceramide Capsules Rapid Skin Renewing Serum 90 Capsules is a retinoid treatment by Elizabeth Arden. Key ingredients include Cyclopentasiloxane, Dimethicone, C12-15 Alkyl Benzoate.
May aggravate: Seborrheic Dermatitis (Shea Butter)
Elizabeth Arden Retinol + HPR Ceramide Capsules Rapid Skin Renewing Serum 60 Capsules is a retinoid treatment by Elizabeth Arden. Key ingredients include Cyclopentasiloxane, Dimethicone, C12-15 Alkyl Benzoate.
May aggravate: Seborrheic Dermatitis (Shea Butter and Glyceryl Stearate); Melasma (Fragrance); Perioral Dermatitis (Fragrance)
Ceramide Retinol + HPR Rapid Skin Renewing Water Cream is a retinoid treatment by Elizabeth Arden. Key ingredients include Caprylic/Capric Triglyceride, Glycerin, Pentylene Glycol.
Luna Retinol Sleeping Night Oil - 0.5 oz is a retinoid treatment by Sunday Riley. Key ingredients include Hydroxypinacolone Retinoate, Rosmarinus Officinalis Leaf Extract, Linalool.
May aggravate: Seborrheic Dermatitis (Glyceryl Stearate and Cetearyl Alcohol)
Granactive Retinoid 2% Emulsion for Wrinkles and Uneven Texture is a retinoid treatment by The Ordinary. Key ingredients include Water, Glycerin, Propanediol.
May aggravate: Seborrheic Dermatitis (Polysorbate 80)
Clinique Smart Clinical Repair™ Wrinkle Correcting Serum is a retinoid treatment by Clinique. Key ingredients include Dimethicone, Butylene Glycol, Glycerin.