oral supplement
EPA/DHA modulate eicosanoid metabolism, shifting prostaglandin production from pro-inflammatory PGE2 (omega-6) to anti-inflammatory PGE3; oral supplementation reduces UV-induced immunosuppression and erythema via COX-2 and NF-κB pathway modulation.
| Concern | Strength | Studies | What the research says |
|---|---|---|---|
| Dryness | Relevant | 1 | Review of omega-3 vs omega-6 balance in skin: EPA/DHA supplementation reduces PGE2 and LTB4 production, improves barrier function, and may reduce UV-induced erythema; evidence strongest for anti-inflammatory skin… |
| Redness & sensitivity | Relevant | 2 | Review of omega-3 vs omega-6 balance in skin: EPA/DHA supplementation reduces PGE2 and LTB4 production, improves barrier function, and may reduce UV-induced erythema; evidence strongest for anti-inflammatory skin… |
No known conflicts — Omega-3 Fatty Acids isn’t flagged against any concern or skin condition.
Strength reflects the ingredient’s effect on each concern; study counts match research whose findings relate to that concern.
Omega-3 Fatty Acids is a oral supplement backed by a moderate body of supporting evidence (evidence tier 2 of 4). We track 3 studies for it, 1 reporting a positive effect.
International Journal of Molecular Sciences · 2020 · systematic review
Review of omega-3 vs omega-6 balance in skin: EPA/DHA supplementation reduces PGE2 and LTB4 production, improves barrier function, and may reduce UV-induced erythema; evidence strongest for anti-inflammatory skin conditions (atopic dermatitis, psoriasis); anti-aging evidence limited to photoprotection endpoints
The American Journal of Clinical Nutrition · 2013 · rct · n=79
Double-blind RCT (n=79): 5 g/day n-3 PUFA (70% EPA) for 3 months reduced solar-simulated-radiation-induced immunosuppression of the nickel contact-hypersensitivity response, but the overall difference was not statistically significant (significant only at the 3.8 J/cm2 dose); red-cell EPA rose 4-fold.
Journal of Investigative Dermatology · 1994 · rct · n=28
Supplementation study (15 volunteers): fish oil 10 g/day (18% EPA, 12% DHA) for 3-6 months more than doubled the UVB minimal erythema dose (sunburn threshold; p<0.01) but increased epidermal lipid peroxidation, suggesting omega-3 acts as an oxidizable buffer.
In 10 products — most often moisturizers (3), serums (3), supplements (3), from $25.07 to $160.00. Set up a profile to rank these for your skin. Click any product to learn more.
Perricone MD
High Potency Classics Hyaluronic Intensive Moisturizer
Moisturizer
$75.0029.6ml · $2.53/ml
Ideal for
Not recommended for
Perricone MD
High Potency Classics Hyaluronic Intensive Moisturizer
Moisturizer
$75.0029.6ml · $2.53/ml
Ideal for
Not recommended for
High Potency Classics Hyaluronic Intensive Moisturizer is a exfoliant by Perricone MD. Key ingredients include Dimethicone, Glycerin, Niacinamide.
Complete your skin profile to see how well this product matches your skin
Set up your skin profileTULA
Protect + Plump Firming & Hydrating Face Moisturizer
Moisturizer
$68.0049.4ml · $1.38/ml
Ideal for
Not recommended for
TULA
Protect + Plump Firming & Hydrating Face Moisturizer
Moisturizer
$68.0049.4ml · $1.38/ml
Ideal for
Not recommended for
Protect + Plump Firming & Hydrating Face Moisturizer is a exfoliant by TULA. Key ingredients include Squalane, Caprylic/Capric Triglyceride, Glycerin.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
jane iredale
jane iredale Skin Ultimate (168 capsules)
Serum
$160.00
Ideal for
Not recommended for
jane iredale
jane iredale Skin Ultimate (168 capsules)
Serum
$160.00
Ideal for
Not recommended for
jane iredale Skin Ultimate (168 capsules) is a antioxidant serum by jane iredale. Key ingredients include Camellia Sinensis Leaf Extract, Omega-3 Fatty Acids, Olive Oil.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
jane iredale
jane iredale Skin Omegas Triple Pack (180 capsules)
Serum
$120.00
Ideal for
jane iredale
jane iredale Skin Omegas Triple Pack (180 capsules)
Serum
$120.00
Ideal for
jane iredale Skin Omegas Triple Pack (180 capsules) is a hydrating serum by jane iredale. Key ingredients include Omega-3 Fatty Acids, Glycerin.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
ANUA
Anua Azelaic Acid 3 Cica Skin Clarifying Toner 250ml
Toner – for Acne & breakouts, Blackheads
$25.07250ml · $0.10/ml
Ideal for
Not recommended for
ANUA
Anua Azelaic Acid 3 Cica Skin Clarifying Toner 250ml
Toner – for Acne & breakouts, Blackheads
$25.07250ml · $0.10/ml
Ideal for
Not recommended for
Anua Azelaic Acid 3 Cica Skin Clarifying Toner 250ml is a exfoliant by ANUA. Key ingredients include Water, 1,2-Hexanediol, Propylene Glycol.
Complete your skin profile to see how well this product matches your skin
Set up your skin profileEducational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.