Journal of Obstetric, Gynecologic & Neonatal Nursing · 2005 · systematic review
Systematic review: Breastfeeding nipple pain evidence consolidation including panthenol as lanolin alternative.
provitamin
Panthenol
Evidencestrong · Tier 1Irritation riskVery lowEffective range0.5–5%In products2,898
Pro-vitamin of pantothenic acid (B5); converted to pantothenic acid in the skin where it functions as a humectant, improves barrier function, and promotes fibroblast proliferation for wound healing.
Concerns it helps
| Concern | Strength | Studies | What the research says |
|---|---|---|---|
| Dryness | Excellent | 8 | Randomized controlled trial (n=60, 2 weeks): Modern post procedure RCT demonstrating significant TEWL reduction and erythema reduction post non ablative fractional laser 1550 1927 nm; panthenol mask included centella… |
| Redness & sensitivity | Strong | 4 | Randomized controlled trial (n=60, 2 weeks): Modern post procedure RCT demonstrating significant TEWL reduction and erythema reduction post non ablative fractional laser 1550 1927 nm; panthenol mask included centella… |
No known conflicts — Panthenol isn’t flagged against any concern or skin condition.
Strength reflects the ingredient’s effect on each concern; study counts match research whose findings relate to that concern.
The research
Panthenol is a provitamin backed by a large, consistent body of clinical evidence (evidence tier 1 of 4). We track 12 studies for it, 9 reporting a positive effect. It is typically effective at 0.5–5% in a formulation.
Read the research — 12 studiesHide the research
Journal of Cosmetic Dermatology · 2025 · rct · n=60
Randomized controlled trial (n=60, 2 weeks): Modern post procedure RCT demonstrating significant TEWL reduction and erythema reduction post non ablative fractional laser 1550 1927 nm; panthenol mask included centella asiatica madecassoside and bisabolol.
Effect of Topically Applied Dexpanthenol on Epidermal Barrier Function and Stratum Corneum Hydration
Q65Arzneimittelforschung · 2011 · rct · n=20
Randomized controlled trial (n=20, 1 weeks): PIVOTAL barrier function evidence demonstrated improved SC hydration and reduced TEWL in two different lipophilic vehicles; foundational modern RCT for panthenol barrier repair.
Contact Dermatitis · 2003 · rct · n=25
Randomized controlled trial (n=25): SLS irritation protection evidence 5% dexpanthenol cream superior to placebo for SC hydration and protection against SLS induced irritation.
American Journal of Clinical Dermatology · 2002 · systematic review · n=25
Review of topical dexpanthenol in skin disorders: summarizes evidence that it improves stratum corneum hydration, reduces transepidermal water loss, stabilizes the skin barrier, and reduces skin irritation and erythema; supports use as an emollient and anti-irritant.
Journal of Dermatological Treatment · 2016 · rct · n=50
Two randomized controlled studies of a panthenol-containing emollient: it significantly improved skin moisturization and accelerated barrier restoration (transepidermal water loss recovery) after experimental skin barrier disruption versus comparator, with beneficial effects on skin microflora.
+ 6 more studies in our evidence base.
Products with Panthenol
In 2,898 products — most often serums (1021), moisturizers (876), cleansers (274), from $2.51 to $1020.00. Set up a profile to rank these for your skin. Click any product to learn more.
10 of 24
Nip + Fab
NIP+FAB Glycolic Daily Pads XXL
Serum
$24.07
★★★★★4.9(920)
Ideal for
- ExcellentDryness
- StrongFine lines & wrinkles
- StrongUneven texture
- StrongDark spots & hyperpigmentation
Not recommended for
MelasmaAtopic Dermatitis / EczemaRosaceaPsoriasisPerioral Dermatitis
Nip + Fab
NIP+FAB Glycolic Daily Pads XXL
Serum
$24.07
★★★★★4.9(920)
Ideal for
- ExcellentDryness
- StrongFine lines & wrinkles
- StrongUneven texture
- StrongDark spots & hyperpigmentation
Not recommended for
MelasmaAtopic Dermatitis / EczemaRosaceaPsoriasisPerioral Dermatitis
NIP+FAB Glycolic Daily Pads XXL is a exfoliant by Nip + Fab. Key ingredients include Water, Glycerin, Glycolic Acid.
Product Ingredients (18)
Irritation risk: unlikely possible likely
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Nip + Fab
NIP+FAB Hyaluronic Fix Extreme4 2% Hydration Concentrate 30ml
Serum
$31.6930ml · $1.06/ml
★★★★★4.9(864)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
- RelevantFine lines & wrinkles
Nip + Fab
NIP+FAB Hyaluronic Fix Extreme4 2% Hydration Concentrate 30ml
Serum
$31.6930ml · $1.06/ml
★★★★★4.9(864)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
- RelevantFine lines & wrinkles
NIP+FAB Hyaluronic Fix Extreme4 2% Hydration Concentrate 30ml is a hydrating serum by Nip + Fab. Key ingredients include Water, Glycerin, Butylene Glycol.
Product Ingredients (11)
Irritation risk: unlikely possible likely
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SkinMedica
SkinMedica AHA/BHA Exfoliating Cleanser (6 fl. oz.)
Exfoliant – for Acne & breakouts, Blackheads
$48.00177.4ml · $0.27/ml
★★★★★4.8(1,084)
Ideal for
- ExcellentDryness
- ExcellentAcne & breakouts
- ExcellentBlackheads
- StrongDark spots & hyperpigmentation
Not recommended for
Atopic Dermatitis / EczemaRosacea
SkinMedica
SkinMedica AHA/BHA Exfoliating Cleanser (6 fl. oz.)
Exfoliant – for Acne & breakouts, Blackheads
$48.00177.4ml · $0.27/ml
★★★★★4.8(1,084)
Ideal for
- ExcellentDryness
- ExcellentAcne & breakouts
- ExcellentBlackheads
- StrongDark spots & hyperpigmentation
Not recommended for
Atopic Dermatitis / EczemaRosacea
SkinMedica AHA/BHA Exfoliating Cleanser (6 fl. oz.) is a exfoliant by SkinMedica. Key ingredients include Cocamidopropyl Betaine, Salicylic Acid, Glycyrrhiza Glabra Root Extract.
Product Ingredients (15)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
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BondiBoost
Serum
$35.55250ml · $0.14/ml
★★★★★4.8(2,158)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
Not recommended for
Seborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma
BondiBoost
Serum
$35.55250ml · $0.14/ml
★★★★★4.8(2,158)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
Not recommended for
Seborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma
BondiBoost Miracle Mask 250ml is a hydrating serum by BondiBoost. Key ingredients include Cetearyl Alcohol, Coco-Caprylate, Glycerin.
Product Ingredients (13)
Irritation risk: unlikely possible likely
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Set up your skin profile
Curlsmith
Curlsmith Double Cream Deep Quencher 237ml
Moisturizer
$22.29237ml · $0.09/ml
★★★★★4.8(769)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
Not recommended for
Seborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma
Curlsmith
Curlsmith Double Cream Deep Quencher 237ml
Moisturizer
$22.29237ml · $0.09/ml
★★★★★4.8(769)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
Not recommended for
Seborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma
Curlsmith Double Cream Deep Quencher 237ml is a basic moisturiser by Curlsmith. Key ingredients include Water, Cetearyl Alcohol, Propanediol.
Product Ingredients (16)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Wella Professionals Care
Wella Professionals Care Oil Reflections Luminous Reboost Mask 150ml
Serum
$29.97150ml · $0.20/ml
★★★★★4.8(1,666)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
Not recommended for
Seborrheic DermatitisAtopic Dermatitis / EczemaRosacea
Wella Professionals Care
Wella Professionals Care Oil Reflections Luminous Reboost Mask 150ml
Serum
$29.97150ml · $0.20/ml
★★★★★4.8(1,666)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
Not recommended for
Seborrheic DermatitisAtopic Dermatitis / EczemaRosacea
Wella Professionals Care Oil Reflections Luminous Reboost Mask 150ml is a antioxidant serum by Wella Professionals Care. Key ingredients include Stearyl Alcohol, Cetyl Alcohol, Panthenol.
Product Ingredients (17)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
BYOMA
BYOMA Hydrating Milky Toner 150ml
Toner – for Dryness, Redness & sensitivity
$15.03150ml · $0.10/ml
★★★★★4.8(1,357)
Ideal for
- ExcellentDryness
- StrongRedness & sensitivity
- StrongFine lines & wrinkles
BYOMA
BYOMA Hydrating Milky Toner 150ml
Toner – for Dryness, Redness & sensitivity
$15.03150ml · $0.10/ml
★★★★★4.8(1,357)
Ideal for
- ExcellentDryness
- StrongRedness & sensitivity
- StrongFine lines & wrinkles
BYOMA Hydrating Milky Toner 150ml is a calming serum by BYOMA. Key ingredients include Water, Butylene Glycol, Glycerin.
Product Ingredients (18)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Vinoperfect Brightening Glycolic Peel Mask 75ml
Exfoliant
$36.8375ml · $0.49/ml
★★★★★4.8(3,016)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
- RelevantBlackheads
- RelevantDark spots & hyperpigmentation
Not recommended for
MelasmaAtopic Dermatitis / EczemaRosaceaPsoriasisPerioral Dermatitis
Caudalie
Caudalie Vinoperfect Brightening Glycolic Peel Mask 75ml
Exfoliant
$36.8375ml · $0.49/ml
★★★★★4.8(3,016)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
- RelevantBlackheads
- RelevantDark spots & hyperpigmentation
Not recommended for
MelasmaAtopic Dermatitis / EczemaRosaceaPsoriasisPerioral Dermatitis
Caudalie Vinoperfect Brightening Glycolic Peel Mask 75ml is a exfoliant by Caudalie. Key ingredients include Glycolic Acid, Panthenol, Dimethicone.
Product Ingredients (11)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Medik8
Serum
$57.1530ml · $1.91/ml
★★★★★4.7(1,389)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
- RelevantFine lines & wrinkles
Medik8
Serum
$57.1530ml · $1.91/ml
★★★★★4.7(1,389)
Ideal for
- ExcellentDryness
- RelevantRedness & sensitivity
- RelevantFine lines & wrinkles
Medik8 Hydr8 B5 Serum 30ml is a hydrating serum by Medik8. Key ingredients include Water, Panthenol, Hyaluronic Acid.
Product Ingredients (6)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Lancôme
Lancôme Confort Hydrating Gentle Sugar Scrub 100ml
Exfoliant
$38.61100ml · $0.39/ml
★★★★★4.7(2,184)
Ideal for
- ExcellentDryness
- ExcellentAcne & breakouts
- ExcellentBlackheads
- RelevantRedness & sensitivity
Not recommended for
Atopic Dermatitis / EczemaRosacea
Lancôme
Lancôme Confort Hydrating Gentle Sugar Scrub 100ml
Exfoliant
$38.61100ml · $0.39/ml
★★★★★4.7(2,184)
Ideal for
- ExcellentDryness
- ExcellentAcne & breakouts
- ExcellentBlackheads
- RelevantRedness & sensitivity
Not recommended for
Atopic Dermatitis / EczemaRosacea
Lancôme Confort Hydrating Gentle Sugar Scrub 100ml is a exfoliant by Lancôme. Key ingredients include Glycerin, Propylene Glycol, Hyaluronic Acid.
Product Ingredients (9)
Irritation risk: unlikely possible likely
Complete your skin profile to see how well this product matches your skin
Set up your skin profileEducational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.