peptide
Endogenous purine nucleoside that activates A2A receptors on fibroblasts and keratinocytes, stimulating collagen and hyaluronic acid synthesis; anti-inflammatory via cAMP pathway.
| Concern | Strength | Studies | What the research says |
|---|---|---|---|
| Fine lines & wrinkles | Strong | 2 | RCT n=126 (crows feet, 3wk); FOITS RCT n=22 periorbital; Korean MFDS functional list |
| Redness & sensitivity | Relevant | — | mechanism (A2A immune-cell receptors); no dedicated RCT |
No known conflicts — Adenosine isn’t flagged against any concern or skin condition.
Strength reflects the ingredient’s effect on each concern; study counts match research whose findings relate to that concern.
Adenosine is a peptide backed by a moderate body of supporting evidence (evidence tier 2 of 4). We track 2 studies for it, 2 reporting a positive effect. It is typically effective at 0.04–0.1% in a formulation.
International Journal of Cosmetic Science · 2006 · rct · n=52
Clinical study using FOITS optical topometry: topical adenosine-containing products significantly improved deep wrinkles around the eyes and between the eyebrows, effective at concentrations as low as 0.1%, supporting adenosine as an anti-wrinkle cosmetic active.
British Journal of Pharmacology · 2016 · in vitro
Mechanistic in-vitro study: adenosine A2A receptor activation promotes collagen (type III) synthesis in human dermal fibroblasts via β-catenin signaling, supporting adenosine's role in stimulating dermal collagen production.
In 1,861 products — most often serums (731), moisturizers (565), eye creams (156), from $2.51 to $1020.00. Set up a profile to rank these for your skin. Click any product to learn more.
Caudalie
Caudalie Premier Cru Skin Barrier Rich Refillable Moisturiser with Bio-Ceramides 50ml
Moisturizer
$107.9550ml · $2.16/ml
Ideal for
Not recommended for
Caudalie
Caudalie Premier Cru Skin Barrier Rich Refillable Moisturiser with Bio-Ceramides 50ml
Moisturizer
$107.9550ml · $2.16/ml
Ideal for
Not recommended for
Caudalie Premier Cru Skin Barrier Rich Refillable Moisturiser with Bio-Ceramides 50ml is a antioxidant serum by Caudalie. Key ingredients include Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Lancôme
Lancôme Génifique Ultimate - Dual Repair Augmented Serum 115ml
Serum
$167.64115ml · $1.46/ml
Ideal for
Not recommended for
Lancôme
Lancôme Génifique Ultimate - Dual Repair Augmented Serum 115ml
Serum
$167.64115ml · $1.46/ml
Ideal for
Not recommended for
Lancôme Génifique Ultimate - Dual Repair Augmented Serum 115ml is a exfoliant by Lancôme. Key ingredients include Glycerin, Pentylene Glycol, Dimethicone.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Resveratrol Lift Retinol Alternative Firming Refillable Night Moisturiser 50ml
Moisturizer – for Dryness, Fine lines & wrinkles
$62.2350ml · $1.25/ml
Ideal for
Not recommended for
Caudalie
Caudalie Resveratrol Lift Retinol Alternative Firming Refillable Night Moisturiser 50ml
Moisturizer – for Dryness, Fine lines & wrinkles
$62.2350ml · $1.25/ml
Ideal for
Not recommended for
Caudalie Resveratrol Lift Retinol Alternative Firming Refillable Night Moisturiser 50ml is a antioxidant serum by Caudalie. Key ingredients include Butylene Glycol, Glycerin, Coco-Caprylate/Caprate.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Resveratrol Lift Retinol Alternative Firming Refillable Cashmere Moisturiser 50ml
Moisturizer – for Dryness, Fine lines & wrinkles
$62.2350ml · $1.25/ml
Ideal for
Not recommended for
Caudalie
Caudalie Resveratrol Lift Retinol Alternative Firming Refillable Cashmere Moisturiser 50ml
Moisturizer – for Dryness, Fine lines & wrinkles
$62.2350ml · $1.25/ml
Ideal for
Not recommended for
Caudalie Resveratrol Lift Retinol Alternative Firming Refillable Cashmere Moisturiser 50ml is a antioxidant serum by Caudalie. Key ingredients include Coco-Caprylate/Caprate, Caprylic/Capric Triglyceride, Butylene Glycol.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Lancôme
Lancôme Génifique Ultimate - Dual Repair Augmented Serum 30ml
Serum
$67.0630ml · $2.23/ml
Ideal for
Not recommended for
Lancôme
Lancôme Génifique Ultimate - Dual Repair Augmented Serum 30ml
Serum
$67.0630ml · $2.23/ml
Ideal for
Not recommended for
Lancôme Génifique Ultimate - Dual Repair Augmented Serum 30ml is a exfoliant by Lancôme. Key ingredients include Glycerin, Pentylene Glycol, Dimethicone.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Resveratrol-Lift Depuffing Eye Cream with Peptides 15ml
Eye Cream – for Dryness, Fine lines & wrinkles
$46.8115ml · $3.12/ml
Ideal for
Caudalie
Caudalie Resveratrol-Lift Depuffing Eye Cream with Peptides 15ml
Eye Cream – for Dryness, Fine lines & wrinkles
$46.8115ml · $3.12/ml
Ideal for
Caudalie Resveratrol-Lift Depuffing Eye Cream with Peptides 15ml is a eye cream by Caudalie. Key ingredients include Butylene Glycol, Glycerin, Coco-Caprylate/Caprate.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Lancôme
Lancôme Rénergie Multi-Lift Night Cream 50ml
Moisturizer
$92.4650ml · $1.85/ml
Ideal for
Not recommended for
Lancôme
Lancôme Rénergie Multi-Lift Night Cream 50ml
Moisturizer
$92.4650ml · $1.85/ml
Ideal for
Not recommended for
Lancôme Rénergie Multi-Lift Night Cream 50ml is a peptide serum by Lancôme. Key ingredients include Glycerin, Caprylic/Capric Triglyceride, Cetyl Alcohol.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Premier Cru Anti-Aging Eye Cream for Fine Lines and Wrinkles 15ml
Eye Cream – for Dryness, Fine lines & wrinkles
$57.1515ml · $3.81/ml
Ideal for
Not recommended for
Caudalie
Caudalie Premier Cru Anti-Aging Eye Cream for Fine Lines and Wrinkles 15ml
Eye Cream – for Dryness, Fine lines & wrinkles
$57.1515ml · $3.81/ml
Ideal for
Not recommended for
Caudalie Premier Cru Anti-Aging Eye Cream for Fine Lines and Wrinkles 15ml is a eye cream by Caudalie. Key ingredients include Mica, Coco-Caprylate/Caprate, Ethylhexyl Stearate.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Premier Cru Anti-Aging Serum with Niacinamide and Hyaluronic Acid 30ml
Serum – for Dryness, Dark spots & hyperpigmentation
$107.9530ml · $3.60/ml
Ideal for
Not recommended for
Caudalie
Caudalie Premier Cru Anti-Aging Serum with Niacinamide and Hyaluronic Acid 30ml
Serum – for Dryness, Dark spots & hyperpigmentation
$107.9530ml · $3.60/ml
Ideal for
Not recommended for
Caudalie Premier Cru Anti-Aging Serum with Niacinamide and Hyaluronic Acid 30ml is a peptide serum by Caudalie. Key ingredients include Glycerin, Propanediol, Niacinamide.
Complete your skin profile to see how well this product matches your skin
Set up your skin profile
Caudalie
Caudalie Resveratrol Lift Instant Firming Refillable Retinol Alternative Serum 30ml
Serum
$66.0430ml · $2.20/ml
Ideal for
Not recommended for
Caudalie
Caudalie Resveratrol Lift Instant Firming Refillable Retinol Alternative Serum 30ml
Serum
$66.0430ml · $2.20/ml
Ideal for
Not recommended for
Caudalie Resveratrol Lift Instant Firming Refillable Retinol Alternative Serum 30ml is a antioxidant serum by Caudalie. Key ingredients include Butylene Glycol, Glycerin, Squalane.
Complete your skin profile to see how well this product matches your skin
Set up your skin profileEducational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.