International Journal of Toxicology · 2017 · systematic review
CIR Expert Panel safety review of dimethiconol and its esters/reaction products, which are used in cosmetics as skin- and hair-conditioning agents. On the basis of the silicones' large molecular size and expectation that they do not penetrate skin, plus available toxicology data, the Panel concluded these ingredients are safe in the present practices of use and concentration.











