retinoid

Retinyl Palmitate

Evidenceemerging · Tier 3Irritation riskVery lowEffective range0.5–2%In products363

Ester form of vitamin A — two enzymatic conversions from retinoic acid. Very stable in formulations but low bioconversion means significantly weaker activity. Best suited for retinoid-naive or sensitive skin.

Concerns it helps

ConcernStrengthStudiesWhat the research says
Fine lines & wrinklesRelevant2Retinyl palmitate has a significantly weaker evidence base than retinol or retinaldehyde. The Green 1998 study of retinyl propionate and scattered retinyl palmitate combination studies provide the main published data.…

No known conflictsRetinyl Palmitate isn’t flagged against any concern or skin condition.

Strength reflects the ingredient’s effect on each concern; study counts match research whose findings relate to that concern.

The research

Retinyl Palmitate is a retinoid backed by early but promising evidence (evidence tier 3 of 4). We track 3 studies for it, 3 reporting a positive effect. It is typically effective at 0.5–2% in a formulation.

Read the research — 3 studies

Frontiers in Pharmacology · 2023 · animal · n=25

In UVB-photoaged mice (with HaCaT-cell support), retinyl palmitate dose-dependently reduced wrinkles and erythema, restored collagen fiber density, downregulated IL-6, IL-1beta and TNF-alpha while upregulating type-I collagen, acting via MAPK and ErbB signaling pathways.

Products with Retinyl Palmitate

In 363 products — most often moisturizers (126), serums (125), sunscreens (48), from $7.62 to $550.45. Set up a profile to rank these for your skin. Click any product to learn more.

10 of 24
Pixi

Pixi

Glow Tonic Serum Exfoliating Radiance Serum

Serum

$24.0029.9ml · $0.80/ml

★★★★★4.9(3,542)

Ideal for

  • StrongFine lines & wrinkles
  • StrongDryness
  • StrongUneven tone & radiance
  • StrongDark spots & hyperpigmentation

Not recommended for

Atopic Dermatitis / EczemaRosaceaPsoriasis

Glow Tonic Serum Exfoliating Radiance Serum is a retinoid treatment by Pixi. Key ingredients include Glycerin, Glycolic Acid, Polysorbate 20.

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RODAN + FIELDS

RODAN + FIELDS

Redefine Intensive Renewing Serum With Retinal

Serum

$100.00

★★★★★4.8(10,968)

Ideal for

  • RelevantFine lines & wrinkles

Redefine Intensive Renewing Serum With Retinal is a retinoid treatment by RODAN + FIELDS. Key ingredients include Cyclopentasiloxane, Dimethicone, C12-15 Alkyl Benzoate.

Product Ingredients (5)

Irritation risk: unlikely possible likely

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Particle for Men

Particle for Men

Particle Neck Cream For Men

Moisturizer

$59.0050ml · $1.18/ml

★★★★★4.8(1,550)

Ideal for

  • ExcellentDryness
  • StrongFine lines & wrinkles
  • StrongUneven texture
  • RelevantRedness & sensitivity

Not recommended for

Acne & breakoutsAtopic Dermatitis / EczemaRosaceaSeborrheic DermatitisPerioral DermatitisPsoriasisMelasma

Particle Neck Cream For Men is a retinoid treatment by Particle for Men. Key ingredients include Water, Propylene Glycol, Cetearyl Alcohol.

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Jack Black

Jack Black

Double Duty Face Moisturizer SPF 20 - 3.3 oz

Sunscreen

$32.0097.6ml · $0.33/ml

★★★★★4.7(1,494)

Ideal for

  • StrongDryness
  • RelevantFine lines & wrinkles

Not recommended for

Rosacea

Double Duty Face Moisturizer SPF 20 - 3.3 oz is a sunscreen by Jack Black. Key ingredients include Avobenzone, Octinoxate, Water.

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RODAN + FIELDS

RODAN + FIELDS

Redefine Overnight Reparative + Moisturizing Lotion

Moisturizer

$85.0029.6ml · $2.87/ml

★★★★★4.7(1,016)

Ideal for

  • ExcellentDryness
  • StrongFine lines & wrinkles
  • RelevantDark spots & hyperpigmentation
  • RelevantRedness & sensitivity

Not recommended for

MelasmaSeborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPsoriasisPerioral Dermatitis

Redefine Overnight Reparative + Moisturizing Lotion is a retinoid treatment by RODAN + FIELDS. Key ingredients include Niacinamide, Cetyl Ethylhexanoate, Glycerin.

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Sand and Sky

Sand and Sky

Australian Pink Clay Porefining Face Mask

Mask

$39.0062.1ml · $0.63/ml

★★★★★4.7(3,958)

Ideal for

  • ExcellentDryness
  • StrongDark spots & hyperpigmentation
  • RelevantUneven texture
  • RelevantFine lines & wrinkles

Not recommended for

Atopic Dermatitis / EczemaRosaceaPsoriasis

Australian Pink Clay Porefining Face Mask is a mask by Sand and Sky. Key ingredients include Water, Glycyrrhiza Glabra Root Extract, Retinyl Palmitate.

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Proactiv

Proactiv

Green Tea Moisturizer

Moisturizer

$36.0088.7ml · $0.41/ml

★★★★★4.7(710)

Ideal for

  • ExcellentDryness
  • RelevantRedness & sensitivity
  • RelevantFine lines & wrinkles

Not recommended for

Acne & breakoutsSeborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma

Green Tea Moisturizer is a retinoid treatment by Proactiv. Key ingredients include Water, Glycerin, Butylene Glycol.

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Tarte Amazonian Clay Bb Tinted Moisturizer Spf 20

Tarte Amazonian Clay Bb Tinted Moisturizer Spf 20

tarte Amazonian Clay BB Tinted Moisturizer SPF 20

Sunscreen

$42.00

★★★★★4.7(1,310)

Ideal for

  • StrongDryness
  • StrongFine lines & wrinkles
  • RelevantDark spots & hyperpigmentation
  • RelevantUneven tone & radiance

Not recommended for

Seborrheic Dermatitis

tarte Amazonian Clay BB Tinted Moisturizer SPF 20 is a sunscreen by Tarte Amazonian Clay Bb Tinted Moisturizer Spf 20. Key ingredients include Titanium Dioxide, Zinc Oxide, Water.

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Luna Daily

Luna Daily

Luna Daily The Everything Oil 30ml

Serum

$30.4830ml · $1.02/ml

★★★★★4.7(718)

Not recommended for

Acne & breakoutsSeborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma

Luna Daily The Everything Oil 30ml is a retinoid treatment by Luna Daily. Key ingredients include Sweet Almond Oil, Coconut Oil, Jojoba Oil.

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ESPA

ESPA

ESPA Overnight Hydration Therapy Cream 55ml

Moisturizer – for Dryness, Fine lines & wrinkles

$52.0755ml · $0.95/ml

★★★★★4.6(505)

Ideal for

  • StrongDryness
  • RelevantFine lines & wrinkles

Not recommended for

Acne & breakoutsSeborrheic DermatitisRosacea

ESPA Overnight Hydration Therapy Cream 55ml is a retinoid treatment by ESPA. Key ingredients include Glycerin, Glyceryl Stearate, Stearyl Alcohol.

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Educational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.