Frontiers in Pharmacology · 2021 · animal
Combining network pharmacology with a DNCB-induced mouse eczema model, German chamomile volatile oil (chamazulene, bisabolol oxides, gamma-elemene) reduced skin inflammation by inhibiting CD4+ Th17 differentiation and MAPK/NF-kB signaling, lowering IL-17, TNF-alpha and IL-6, improving skin hydration and reducing mast-cell infiltration.









