DermIQ

preservative

Methylchloroisothiazolinone

Evidencestrong · Tier 1Irritation riskHighIn products45

Chloro-isothiazolinone preservative (with MI = Kathon CG); top-10 contact allergen.

The research

Methylchloroisothiazolinone is a preservative backed by a large, consistent body of clinical evidence (evidence tier 1 of 4). We are still building the study record for this ingredient.

Products with Methylchloroisothiazolinone

In 45 products — most often cleansers (23), serums (17), exfoliants (2), from $14.50 to $114.30. Set up a profile to rank these for your skin. Click any product to learn more.

10 of 24
Natura

Natura

Natura Bissé Stabilizing Facial Cleansing Gel with AHA and PHA 200ml

Exfoliant

$67.31200ml · $0.34/ml

★★★★★4.6(580)
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Ideal for

  • ExcellentDryness
  • ExcellentRedness & sensitivity
  • StrongDark spots & hyperpigmentation
  • StrongUneven texture

Not recommended for

Atopic Dermatitis / EczemaPerioral DermatitisPsoriasisMelasmaRosacea

Natura Bissé Stabilizing Facial Cleansing Gel with AHA and PHA 200ml is a exfoliant by Natura. Key ingredients include Sodium Laureth Sulfate, Cocamidopropyl Betaine, Glycolic Acid.

Product Ingredients (22)

Irritation risk: unlikely possible likely
Sodium Laureth SulfateCocamidopropyl BetaineGlycolic AcidLactic AcidSodium HydroxideCitric AcidAllantoinPolysorbate 20Sodium Lauryl SulfateNiacinamidePanthenolPropylene GlycolSodium CitrateFragranceLimoneneGeraniolHydroxycitronellalLinaloolCitronellolMethylchloroisothiazolinoneMethylisothiazolinonePhenoxyethanol

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Philosophy

Philosophy

Clear Days Ahead Oil-Free Salicylic Acid Acne Treatment Cleanser

Cleanser

$29.00236.6ml · $0.12/ml

★★★★★4.2(1,248)
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Ideal for

  • ExcellentDryness
  • ExcellentAcne & breakouts
  • ExcellentBlackheads
  • StrongRedness & sensitivity

Not recommended for

Atopic Dermatitis / EczemaRosacea

Clear Days Ahead Oil-Free Salicylic Acid Acne Treatment Cleanser is a water cleanser by Philosophy. Key ingredients include Salicylic Acid, Water, Cocamidopropyl Betaine.

Product Ingredients (13)

Irritation risk: unlikely possible likely
Salicylic Acid1%WaterCocamidopropyl BetainePolysorbate 20NiacinamideGlycerinPanthenolButylene GlycolCitric AcidSodium HydroxidePropylene GlycolMethylchloroisothiazolinoneMethylisothiazolinone

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Clinique

Clinique

Clinique Liquid Facial Soap Mild 200ml

Serum

$29.21200ml · $0.15/ml

★★★★★4.5(408)
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Ideal for

  • RelevantDryness
  • RelevantFine lines & wrinkles

Not recommended for

Atopic Dermatitis / EczemaPerioral DermatitisPsoriasis

Clinique Liquid Facial Soap Mild 200ml is a antioxidant serum by Clinique. Key ingredients include Sodium Laureth Sulfate, Hyaluronic Acid, Citric Acid.

Product Ingredients (11)

Irritation risk: unlikely possible likely
Sodium Laureth SulfateHyaluronic AcidCitric AcidButylene GlycolCaprylyl GlycolVitamin EDisodium EDTAPhenoxyethanolSodium BenzoateMethylchloroisothiazolinoneMethylisothiazolinone

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Estée Lauder

Estée Lauder

Estée Lauder Perfectly Clean MultiAction Foam Cleanser and Purifying Mask 150ml

Cleanser

$44.45150ml · $0.30/ml

★★★★★4.7(305)
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Ideal for

  • StrongDryness
  • RelevantFine lines & wrinkles

Not recommended for

Acne & breakoutsSeborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma

Estée Lauder Perfectly Clean MultiAction Foam Cleanser and Purifying Mask 150ml is a water cleanser by Estée Lauder. Key ingredients include Myristic Acid, Glycerin, Palmitic Acid.

Product Ingredients (11)

Irritation risk: unlikely possible likely
Myristic AcidGlycerinPalmitic AcidLauric AcidStearic AcidAlgae ExtractHyaluronic AcidFragranceDisodium EDTAMethylchloroisothiazolinoneMethylisothiazolinone

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Beauty Works

Beauty Works

Beauty Works Pearl Nourishing Argan Oil Mask 250ml

Serum

$17.13250ml · $0.07/ml

★★★★★4.7(270)
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Not recommended for

Atopic Dermatitis / EczemaRosaceaSeborrheic Dermatitis

Beauty Works Pearl Nourishing Argan Oil Mask 250ml is a skincare product by Beauty Works. Key ingredients include Titanium Dioxide, Propylene Glycol, Argan Oil.

Product Ingredients (9)

Irritation risk: unlikely possible likely
Titanium DioxidePropylene GlycolArgan OilLinaloolHexyl CinnamalCitric AcidLimoneneMethylchloroisothiazolinoneMethylisothiazolinone

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Perricone MD

Perricone MD

Vitamin C Ester Citrus Brightening Cleanser

Cleanser

$39.00177.4ml · $0.22/ml

★★★★★4.5(282)
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Not recommended for

Redness & sensitivityAtopic Dermatitis / EczemaPerioral DermatitisPsoriasisRosaceaMelasma

Vitamin C Ester Citrus Brightening Cleanser is a water cleanser by Perricone MD. Key ingredients include Sodium Laureth Sulfate, Decyl Glucoside, Cocamidopropyl Betaine.

Product Ingredients (10)

Irritation risk: unlikely possible likely
Sodium Laureth SulfateDecyl GlucosideCocamidopropyl BetaineDisodium EDTACitric AcidSulisobenzoneMethylchloroisothiazolinoneMethylisothiazolinoneFragranceLimonene

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Clinique

Clinique

Clinique Liquid Facial Soap Oily Skin Formula 200ml

Serum

$29.21200ml · $0.15/ml

★★★★★4.3(276)
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Not recommended for

Atopic Dermatitis / EczemaPerioral DermatitisPsoriasis

Clinique Liquid Facial Soap Oily Skin Formula 200ml is a skincare product by Clinique. Key ingredients include Sodium Laureth Sulfate, Butylene Glycol, Citric Acid.

Product Ingredients (8)

Irritation risk: unlikely possible likely
Sodium Laureth SulfateButylene GlycolCitric AcidCaprylyl GlycolDisodium EDTAMethylchloroisothiazolinoneMethylisothiazolinonePhenoxyethanol

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Clinique for Men

Clinique for Men

Clinique For Men Face Wash 200ml

Cleanser

$29.72200ml · $0.15/ml

★★★★★4.7(86)
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Ideal for

  • RelevantDryness
  • RelevantFine lines & wrinkles

Not recommended for

Atopic Dermatitis / EczemaPerioral DermatitisPsoriasis

Clinique For Men Face Wash 200ml is a water cleanser by Clinique for Men. Key ingredients include Sodium Laureth Sulfate, Hyaluronic Acid, Butylene Glycol.

Product Ingredients (11)

Irritation risk: unlikely possible likely
Sodium Laureth SulfateHyaluronic AcidButylene GlycolCaprylyl GlycolCitric AcidVitamin EDisodium EDTASodium BenzoatePhenoxyethanolMethylchloroisothiazolinoneMethylisothiazolinone

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Origins

Origins

Origins Checks and Balances Frothy Face Wash 150ml

Cleanser

$29.21150ml · $0.20/ml

★★★★★4.7(74)
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Ideal for

  • StrongDryness

Not recommended for

Acne & breakoutsSeborrheic DermatitisRosaceaAtopic Dermatitis / Eczema

Origins Checks and Balances Frothy Face Wash 150ml is a water cleanser by Origins. Key ingredients include Myristic Acid, Glycerin, Palmitic Acid.

Product Ingredients (10)

Irritation risk: unlikely possible likely
Myristic AcidGlycerinPalmitic AcidLauric AcidStearic AcidLinaloolCetearyl AlcoholButylene GlycolDisodium EDTAMethylchloroisothiazolinone

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Estée Lauder

Estée Lauder

Estée Lauder Perfectly Clean Multi-action Foam Cleanser/Purifying Mask

Cleanser – for Dryness, sagging

$32.00

★★★★★4.5(70)
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Ideal for

  • StrongDryness
  • RelevantFine lines & wrinkles

Not recommended for

Acne & breakoutsSeborrheic DermatitisAtopic Dermatitis / EczemaRosaceaPerioral DermatitisPsoriasisMelasma

Estée Lauder Perfectly Clean Multi-action Foam Cleanser/Purifying Mask is a water cleanser by Estée Lauder. Key ingredients include Myristic Acid, Glycerin, Palmitic Acid.

Product Ingredients (11)

Irritation risk: unlikely possible likely
Myristic AcidGlycerinPalmitic AcidLauric AcidStearic AcidAlgae ExtractHyaluronic AcidFragranceDisodium EDTAMethylchloroisothiazolinoneMethylisothiazolinone

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Educational information, not medical advice. Study findings summarise the cited research and may not reflect every formulation.