Pharmaceutics · 2023 · in vitro
Encapsulating retinol propionate and hydroxypinacolone retinoate in supramolecular nanoparticles gave high stability, low irritation and sustained release; the formulation significantly increased type I collagen synthesis in human dermal fibroblasts (p<0.01), and facial imaging showed visibly reduced wrinkles over 56 days of use.



