Ferulic Acid Use for Skin Applications: A Systematic Review
Q85Journal of Clinical and Aesthetic Dermatology · 2024 · systematic review · n=443
Systematic review (n=443): MODERN systematic review consolidating 18 human studies 443 patients evaluating ferulic acid effect on skin erythema n 13 pigmentation n 9 hydration n 7 elasticity n 6 and texture n 6; demonstrates FA effective both alone and in combination for multiple cutaneous conditions.
Skin Pharmacology and Physiology · 2018 · systematic review
Review of ferulic acid in cosmetics: potent antioxidant (scavenges superoxide, hydroxyl, and peroxyl radicals), UV absorber (λmax 316-322 nm), anti-inflammatory, and collagen-protective; enhances stability and efficacy of co-formulated vitamin C and E; optimal cosmetic concentration 0.5-1.0%
Dermatologic Therapy · 2022 · observational · n=20
Clinical study (n=20): MONOTHERAPY evidence 14% ferulic acid peel demonstrated improvements in skin hydration topography melanin levels and erythema; INDEPENDENT NON INDUSTRY FUNDED evidence from Polish research group outside Pinnell Duke SkinCeuticals evidence base; emerging standalone evidence for ferulic acid beyond combination use.
Efficacy of ferulic acid in improving the appearance of photoaged skin
Q40Cosmetic Dermatology · 2008 · observational
Clinical study: Early monotherapy evidence demonstrating ferulic acid improves appearance of photoaged skin independently of C E combination.
International Journal of Pharmaceutics · 2000 · in vitro
In vitro and in vivo evaluation of ferulic (and caffeic) acid as topical photoprotectants: ferulic acid absorbs UV light and scavenges free radicals, and topical application reduced UV-induced oxidative skin damage in vivo, supporting its use as an antioxidant photoprotective agent.
Annals of Dermatology · 2016 · in vitro
In-vitro/mechanistic study: Demonstrates ferulic acid pretreatment protects human dermal fibroblasts against UVA irradiation; mechanism evidence for dermal collagen protection indication.
+ 5 more studies in our evidence base.